Read e-book online A History of the End of the World: How the Most PDF

By Jonathan Kirsch

"[The ebook of] Revelation has served as a "language arsenal" in an excellent some of the social, cultural, and political conflicts in Western historical past. repeatedly, Revelation has stirred a few risky women and men to behave out their very own deepest apocalypses. notably, the ethical calculus of Revelation—the demonization of one's enemies, the sanctification of revenge taking, and the thought that background needs to lead to catastrophe—can be detected in a number of the worst atrocities and excesses of all ages, together with our personal. For all of those purposes, the remainder of us forget about the ebook of Revelation basically at our impoverishment and, extra to the purpose, at our personal peril."

The mysterious writer of the ebook of Revelation (or the Apocalypse, because the final e-book of the recent testomony can be identified) by no means thought of that his sermon at the drawing close finish instances may final past his personal existence. in reality, he envisioned that the destruction of the earth will be witnessed via his contemporaries. but Revelation not just outlived its writer; this brilliant and violent revenge delusion has performed an important position within the march of Western civilization.

Ever considering the fact that Revelation was once first preached because the published note of Jesus Christ, it has haunted and encouraged hearers and readers alike. The mark of the beast, the Antichrist, 666, the Whore of Babylon, Armageddon, and the 4 Horsemen of the Apocalypse are only a number of the photographs, words, and codes that experience burned their manner into the material of our tradition. The questions raised pass instantly to the guts of the human worry of demise and obsession with the afterlife. do we, separately or jointly, journey off to glory, or can we drown in hellfire for all eternity? As those that most sensible manage this darkish imaginative and prescient realized, which aspect we fall on is usually a subject of lifestyles or loss of life. Honed right into a weapon within the ongoing tradition wars among states, religions, and citizenry, Revelation has considerably altered the process background.

Kirsch, whom the Washington Post calls "a tremendous storyteller with an inherent ability for rendering historical stories appropriate and attractive to fashionable audiences," grants a far-ranging, pleasing, and surprising background of this scandalous ebook, which used to be approximately minimize from the recent testomony. From the autumn of the Roman Empire to the Black dying, the Inquisition to the Protestant Reformation, the hot global to the increase of the spiritual correct, this chronicle of the use and abuse of the ebook of Revelation tells the story of the unfolding of background and the hopes, fears, goals, and nightmares of all humanity.

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Qxd 11/17/2008 12:25 PM Page 49 A Novel Method for DNA Microarray Data Analysis 49 (a) (b) Number of Genes with |FC|>2 700 631 600 500 P190 400 P210 300 200 100 119 179 P230 0 Fig. 6. (a) Interface of the software tool. (b) Number of genes with the absolute fold change value >2. (c) Number of genes upregulated with the fold change value >2. (d) Number of genes downregulated with the fold change value <−2. qxd 50 11/17/2008 12:25 PM Page 50 DNA Microarray Technology and Data Analysis in Cancer Research (c) Number of Genes with FC>2 380 400 350 300 250 P190 200 P210 150 P230 115 94 100 50 0 (d) Number of Genes with FC<-2 300 251 250 200 P190 150 P210 P230 100 64 50 25 0 Fig.

Finally, the top 1000 genes with the most expressions are selected from P190, P210, and P230, respectively, for a comparison in Fig. 5. In order to analyze the microarray expression data for our experiments efficiently and accurately, a PC-based software application (Gene Star) has been developed. The user-friendly graphical interface of Gene Star for data analysis and display is shown in Fig. 6(a). Further comparisons have been carried out and significant results have emerged based on the observations: • As shown in Figs.

4. e. correlation) of samples within a group to the degree of similarity of samples between groups. Arrays are plotted in groups according to sample type (Figs. 7). qxd 11/17/2008 12:25 PM Page 31 Current Analytical Methods of DNA Microarray Data 31 Fig. 11. Histogram of the distribution of Fs permutation p-values resulting from the contrast of iterPLIER-processed data for sample groups Mut_A versus B6 (top left), Mut_A versus Vector (top right), and Vector versus B6 (bottom center). 5. Average MA plot of normalized intensities MA plots are used to visualize the similarity of groups of samples.

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