By Andrea Lania MD, PHD (auth.), Brooke Swearingen MD, Beverly M. K. Biller MD (eds.)
This textual content offers a close replace on present diagnostic and healing thoughts invaluable within the administration of a vast spectrum of pituitary issues. The contents replicate the multidisciplinary method wanted for sufferers with issues of the pituitary gland, with contributions from either endocrinologists and neurosurgeons, in addition to uniqueness contributions from radiologists, ophthalmologists, pathologists, radiation oncologists, and neurologists. The ebook specializes in each one pituitary tumor subtype, and comprises extra chapters on the topic of different lesions of the sella, together with tumor administration while pregnant and within the pediatric age group.
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Additional info for Diagnosis and Management of Pituitary Disorders
Consequently, part of the evaluation of any sellar mass, and especially those > 1 cm in diameter, should include determination of the deficiencies of any hormones secreted or controlled by the pituitary. m. on more than one occasion, testosterone in men, and estradiol in women of premenopausal age. Following treatment, these functions should be reevaluated and, if persistent, treated. , diabetes insipidus, is important not only because it needs to be treated if present but because its presence helps identify the type of sellar mass.
Prolactinoma composed of cells with chromophobic cytoplasm arranged in a diffuse architectural pattern (A). Prolactinoma with small, hyperchromatic cells after dopamine agonist therapy (B). Positive immunohistochemical reaction for PRL with diffuse (C) and paranuclear patterns (D) in two prolactinomas. 2. GH-Producing Adenomas Definition: Pituitary adenomas producing GH in excess and clinically associated with gigantism in young patients and acromegaly in adults. Adenomas expressing GH immunohistochemically without clinical evidence of overproduction are very rare.
Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM. The descriptive epidemiology of craniopharyngioma. J Neurosurg 1998;89:547–51. 16. Cossu-Rocca P, Jones TD, Roth LM, et al. Cytokeratin and CD30 expression in dysgerminoma. Hum Pathol 2006;37:1015–21. 17. Schaller B, Kirsch E, Tolnay M, Mindermann T. Symptomatic granular cell tumor of the pituitary gland: case report and review of the literature. Neurosurgery 1998;42:166–70. 18. Kasashima S, Oda Y, Nozaki J, Shirasaki M, Nakanishi I.